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XPC-7724

XPC-7724 is a selective Nav1.6 channel inhibitor with a IC50 value of 0.078 μM. XPC-7724 can be used in the study of neurological diseases[1].

Product Specifications

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/xpc-7724.html

Concentration

10mM

Purity

99.51

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=C(C=C(C(S(=O)(NC2=NC=CC=N2)=O)=C1)F)N(C3CCN(CC3)[C@@H](C4=CC=CC=C4)C)C

Molecular Formula

C25H30FN5O2S

Molecular Weight

483.60

References & Citations

[1]Goodchild SJ, et al. Molecular Pharmacology of Selective NaV1.6 and Dual NaV1.6/NaV1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo. ACS Chem Neurosci. 2024 Feb 15.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Nav1.6

Available Sizes

Curated Selection

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