XPC-7724
XPC-7724 is a selective Nav1.6 channel inhibitor with a IC50 value of 0.078 μM. XPC-7724 can be used in the study of neurological diseases[1].
Product Specifications
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/xpc-7724.html
Concentration
10mM
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C=C(C(S(=O)(NC2=NC=CC=N2)=O)=C1)F)N(C3CCN(CC3)[C@@H](C4=CC=CC=C4)C)C
Molecular Formula
C25H30FN5O2S
Molecular Weight
483.60
References & Citations
[1]Goodchild SJ, et al. Molecular Pharmacology of Selective NaV1.6 and Dual NaV1.6/NaV1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo. ACS Chem Neurosci. 2024 Feb 15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.6
Available Sizes
Curated Selection
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