Levosulpiride-d3

Levosulpiride-d3 is the deuterium labeled Levosulpiride. Levosulpiride (RV-12309) is the (S) -enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class[1][2].

Product Specifications

CAS Number

[124020-27-5]

Product Name Alternative

RV-12309-d3; S- (-) -Sulpiride-d3

UNSPSC

12352005

Target

5-HT Receptor; Dopamine Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease; Neurological Disease

Purity

99.79

Solubility

10 mM in DMSO|DMSO : 50mg/mL (ultrasonic)

Smiles

C(NC[C@H]1N(CC)CCC1)(=O)C2=C(OC([2H])([2H])[2H])C=CC(S(N)(=O)=O)=C2

Molecular Formula

C15H20D3N3O4S

Molecular Weight

344.44

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Triebel J, et al. From Bench to Bedside: Translating the Prolactin/Vasoinhibin Axis. Front Endocrinol (Lausanne) . 2017;8:342. Published 2017 Dec 11.