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Parvalbumin Antibody: ATTO 488

Mouse Anti-Rat parvalbumin Monoclonal IgG2a

Product Specifications

Background

Parvalbumin is involved in calcium signaling. Alterations in the function of parvalbumin-expressing neurons have been implicated in Alzheimer's, autism, schizophrenia, age-related cognitive defects and some forms of cancer (1).

Specifications

Detects 12 kDa.

Product Name Alternative

Parvalbumin alpha antibody, PRVA_HUMAN antibody, PVALB antibody

Synonyms

parvalbumin Antibody, Clone C12: ATTO 488

UNSPSC

12352203

Gene ID

25269

Swiss Prot

P02625

Accession Number

NP_071944.1

Cellular Locus

Cytoplasmic vesicle membrane

Host

Mouse

Species Reactivity

Human,Rat,Mouse

Immunogen

Synthetic peptide from the full length Rat Parvalbumin protein

Target

parvalbumin

Clonality

Monoclonal

Isotype

IgG2a

Clone

C12

Conjugation

ATTO 488

Tissue Specificity

Retina. Expressed throughout the horizontal cells and/or terminals.

Validated Applications

IHC,ICC/IF

Purification

Protein A Purified

Limit Of Detection

A 1:500 dilution of SMC-563 was sufficient for detection of Parvalbumin in 15 ug of Rat Brain by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:500); IHC (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Cates. M.S., Teodoro M.L., Phillips G.N. (2002) Biophys J. 82(3): 1133-1146.

Product Datasheet

https://cdn.gentaur.com/products/400/4294322/datasheet/smc-563d-a488.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4294322/msds/smc-563d-a488.pdf

CAS Number

9007-83-4

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