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Neuroligin 4 Antibody

Mouse Anti-Mouse Neuroligin 4 Monoclonal IgG1

Product Specifications

Background

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.

Specifications

Detects ~125-130kDa. Does not cross-react with other Neuroligins.

Product Name Alternative

ASPGX2 Antibody, AUTSX2 Antibody, HLNX Antibody, HNLX Antibody, KIAA1260 Antibody, MGC22376 Antibody, NLGN Antibody, NLGN4 Antibody, NLGN4X Antibody, neuroligin-4 X-linked Antibody, neuroligin X Antibody, neuroligin 4 Antibody, X-linked Antibody

Synonyms

Neuroligin 4 Antibody, Clone N98/7

UNSPSC

12352203

Gene ID

100113365

Swiss Prot

B0F2B4

Accession Number

ABS19580

Cellular Locus

Cell Membrane | Cell Junction

Host

Mouse

Species Reactivity

Mouse,Rat

Immunogen

Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ~45% identity with Neuroligin-1, -2 and -3.

Target

Neuroligin 4

Clonality

Monoclonal

Isotype

IgG1

Clone

N98/7 (Formerly sold as S98-7)

Conjugation

Unconjugated

Validated Applications

WB,IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-469 was sufficient for detection of Neuroligin 4 in 20 µg of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.012

Buffer

PBS pH7.4, 50% glycerol, 0.1% sodium azide

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product MSDS

https://cdn.gentaur.com/products/400/4292269/msds/smc-469s.pdf

CAS Number

9007-83-4

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