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Neuroligin 4 Antibody: APC

Mouse Anti-Mouse Neuroligin 4 Monoclonal IgG1

Product Specifications

Background

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.

Specifications

Detects ~125-130kDa. Does not cross-react with other Neuroligins.

Product Name Alternative

ASPGX2 Antibody, AUTSX2 Antibody, HLNX Antibody, HNLX Antibody, KIAA1260 Antibody, MGC22376 Antibody, NLGN Antibody, NLGN4 Antibody, NLGN4X Antibody, neuroligin-4 X-linked Antibody, neuroligin X Antibody, neuroligin 4 Antibody, X-linked Antibody

Synonyms

Neuroligin 4 Antibody, Clone N98/7 : APC

UNSPSC

12352203

Gene ID

100113365

Swiss Prot

B0F2B4

Accession Number

ABS19580

Cellular Locus

Cell Membrane | Cell Junction

Host

Mouse

Species Reactivity

Mouse,Rat

Immunogen

Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ~45% identity with Neuroligin-1, -2 and -3.

Target

Neuroligin 4

Clonality

Monoclonal

Isotype

IgG1

Clone

N98/7 (Formerly sold as S98-7)

Conjugation

APC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-469 was sufficient for detection of Neuroligin 4 in 20 µg of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product Datasheet

https://cdn.gentaur.com/products/400/4292255/datasheet/smc-469d-apc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4292255/msds/smc-469d-apc.pdf

CAS Number

9007-83-4

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