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QKI (pan) Antibody: RPE

Mouse Anti-Human QKI (pan) Monoclonal IgG2b

Product Specifications

Background

QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.

Specifications

Detects ~36-38kDa.

Product Name Alternative

Protein quaking Antibody, Hqk Antibody, HqkI Antibody, QKI Antibody, KH Domain Containing Antibody, RNA Binding (QKI) Antibody

Synonyms

QKI Antibody, Clone N147/6: RPE

UNSPSC

12352203

Gene ID

9444

Swiss Prot

Q96PU8

Accession Number

NP_006766.1.

Cellular Locus

Cytoplasm | Nucleus

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.

Target

QKI

Clonality

Monoclonal

Isotype

IgG2b

Clone

N147/6 (Formerly sold as S147-6)

Conjugation

RPE

Validated Applications

WB,IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-467 was sufficient for detection of Pan-QKI in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product Datasheet

https://cdn.gentaur.com/products/400/4292217/datasheet/smc-467d-rpe.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4292217/msds/smc-467d-rpe.pdf

CAS Number

9007-83-4

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