Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mitofusin 2 Antibody: HRP

Mouse Anti-Human Mitofusin 2 Monoclonal IgG2a

Product Specifications

Background

Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.

Specifications

Detects ~90kDa. No cross-reactivity against Mitofusin-1.

Product Name Alternative

CMT2A Antibody, CMT2A2 Antibody, CPRP 1 Antibody, CPRP1 Antibody, Fzo Antibody, HSG Antibody, hyperplasia suppressor gene Antibody, Hypertension related protein 1 Antibody, KIAA0214 Antibody, MARF Antibody, MFN 2 Antibody, Mfn2 Antibody, Mitochondrial assembly regulatory factor Antibody, Mitofusin-2 Antibody, Mitofusin2 Antibody, Transmembrane GTPase MFN2 Antibody

Synonyms

Mitofusin 2 Antibody, Clone N153/5: HRP

UNSPSC

12352203

Gene ID

170731

Swiss Prot

Q80U63

Accession Number

NP_573464.2

Cellular Locus

Mitochondrion | Mitochondrion Outer Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical). Human: 92% identity (214/231 amino acids identical) ~55% identity with Mitofusin-1.

Target

Mitofusin 2

Clonality

Monoclonal

Isotype

IgG2a

Clone

N153/5 (Formerly sold as S153-5)

Conjugation

HRP

Validated Applications

WB,IHC,ELISA

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-457 was sufficient for detection of Mitofusin-2 in 20 µg of mouse cardiac mitochondrial lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product Datasheet

https://cdn.gentaur.com/products/400/4292014/datasheet/smc-457d-hrp.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4292014/msds/smc-457d-hrp.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mmp28 Mouse qPCR Primer Pair (NM_080453)
MP207900 200 Reactions

Mmp28 Mouse qPCR Primer Pair (NM_080453)

Ask
View Details
GNB4 AAV Vector (Mouse) (CMV)
22315104 1 μg

GNB4 AAV Vector (Mouse) (CMV)

Ask
View Details
RPL12P14 3'UTR Lenti-reporter-Luc Vector
40765081 1.0 μg

RPL12P14 3'UTR Lenti-reporter-Luc Vector

Ask
View Details
E/IMO301-SA-PHOLUMB-150x150/1-B AC Signs
195455 Pack of 1 Pictogram(s)

E/IMO301-SA-PHOLUMB-150x150/1-B AC Signs

Ask
View Details
Recombinant Syncephalastrum racemosum Kinesin heavy chain, partial
MBS1000994 Inquire

Recombinant Syncephalastrum racemosum Kinesin heavy chain, partial

Ask
View Details
C17orf85 Protein Vector (Human) (pPM-C-HA)
14011021 500 ng

C17orf85 Protein Vector (Human) (pPM-C-HA)

Ask
View Details