Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LRRK2/Dardarin Antibody: FITC

Mouse Anti-Human LRRK2/Dardarin Monoclonal IgG1

Product Specifications

Background

LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features.

Specifications

Detects >200kDa.

Product Name Alternative

Leucine-rich repeat kinase 2 Antibody, RIP7 Antibody, PARK8 Antibody, Dardarin Antibody, ROCO 2 Antibody, RIPK7 Antibody, Leucine-rich repeat serine/threonine-protein kinase 2 Antibody, augmented in rheumatoid arthritis 17 Antibody

Synonyms

LRRK2/Dardarin Antibody, Clone N138/6: FITC

UNSPSC

12352203

Gene ID

120892

Swiss Prot

Q5S007

Accession Number

NP_940980

Cellular Locus

Cytoplasm | Membrane | Mitochondrion | Golgi Apparatus | Cell Projection | Axon | Dendrite | Endoplasmic Reticulum | Cytoplasmic Vesicle | Endosome | Lysosome

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein, amino acids 1-500 (N-terminus) of human LRRK2. 83% identical in mouse and rat. No significant identity with LRRK1.

Target

LRRK2

Clonality

Monoclonal

Isotype

IgG1

Clone

N138/6 (Formerly sold as S138-6)

Conjugation

FITC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-446 was sufficient for detection of LRRK2/Dardarin in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product Datasheet

https://cdn.gentaur.com/products/400/4291738/datasheet/smc-446d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4291738/msds/smc-446d-fitc.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal Chromogranin A Antibody (LK2H10 + PHE5) [DyLight 350]
NBP2-34673UV 0.1 mL

Mouse Monoclonal Chromogranin A Antibody (LK2H10 + PHE5) [DyLight 350]

Ask
View Details
Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)
MBS1395559-01 0.02 mg (E-Coli)

Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)

Ask
View Details
Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)
MBS1395559-02 0.1 mg (E-Coli)

Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)

Ask
View Details
Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)
MBS1395559-03 0.02 mg (Yeast)

Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)

Ask
View Details
Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)
MBS1395559-04 0.1 mg (Yeast)

Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)

Ask
View Details
Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)
MBS1395559-05 0.02 mg (Baculovirus)

Recombinant Borrelia afzelii Phosphopantetheine adenylyltransferase (coaD)

Ask
View Details