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Alpha-2C Adrenergic Receptor Antibody

Mouse Anti-Human Alpha-2C Adrenergic Receptor Monoclonal IgG1

Product Specifications

Background

The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.

Specifications

Detects 50kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.

Product Name Alternative

Adra 2c Antibody, Alpha-2CAR Antibody, ADRA2C Antibody, ADRA2L2 Antibody, ADRARL2 Antibody, Alpha 2CAR Antibody, alpha2 AR C4 Antibody, alpha2 C4 Antibody, alpha2C Antibody, ALPHA2CAR Antibody, Alpha-2 adrenergic receptor subtype C4 Antibody, Alpha-2C adrenoreceptor Antibody, Adrenergic alpha 2C receptor Antibody, Alpha 2C adrenergic receptor Antibody, Alpha 2C adrenergic receptor subtype C4 Antibody, Alpha 2C adrenoceptor Antibody, Alpha 2C adrenoreceptor Antibody, Alpha-2-adrenergic receptor Antibody, renal type Antibody, alpha2cii-adrenergic receptor Antibody, Subtype alpha2 C4 Antibody

Synonyms

Alpha2C Adrenergic Antibody, Clone N330A/80

UNSPSC

12352203

Gene ID

152

Swiss Prot

P18825

Accession Number

NP_000674.2

Cellular Locus

Cell Membrane

Host

Mouse

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor

Target

Alpha2C Adrenergic

Clonality

Monoclonal

Isotype

IgG1

Clone

N330A/80 (Formerly sold as S330A-80)

Conjugation

Unconjugated

Validated Applications

WB,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-435 was sufficient for detection of Alpha2C Adrenergic Receptor in 20 µg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.012

Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Filipeanu C.M., et al. (2011) Biochim Biophys Acta. 1813: 346-357. 2. Powe D.G., et al. (2011) Breast Cancer Res Treat. 130: 457-463.

Product MSDS

https://cdn.gentaur.com/products/400/4291469/msds/smc-435s.pdf

CAS Number

9007-83-4

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