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GluN2A/NR2A Antibody: ATTO 488

Mouse Anti-Rat GluN2A/NR2A Monoclonal IgG2b

Product Specifications

Background

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D).

Specifications

Detects ~170kDa. Does not react with NR2B.

Product Name Alternative

NMDA 2A Antibody, NMDAR2A Antibody, NMDAR 2A Antibody, NMDA Receptor 2A Antibody, Glutamate Receptor Antibody, GRIN2A Antibody, Glutamate [NMDA] Receptor subunit epsilon-1 Antibody, Glutamate receptor ionotropic N methyl D aspartate 2A Antibody, HNR2A Antibody, N methyl D aspartate receptor channel Antibody, subunit epsilon 1 Antibody, N Methyl D Aspartate Receptor Subtype 2A Antibody, N methyl D aspartate receptor subunit 2A Antibody, NMDA receptor subtype 2A Antibody, NMDA Receptor Type 2A Antibody, OTTHUMP00000160135 Antibody, OTTHUMP00000174531 Antibody

Synonyms

GluN2A/NR2A Antibody, Clone N327A/38: ATTO 488

UNSPSC

12352203

Gene ID

24409

Swiss Prot

Q00959

Accession Number

NP_036705.3

Cellular Locus

Cell Membrane | Cell Junction

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A

Target

NR2A

Clonality

Monoclonal

Isotype

IgG2b

Clone

N327A/38 (Formerly sold as S327A-38)

Conjugation

ATTO 488

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-434 was sufficient for detection of GluN2A/NR2A in 20 µg of COS cells transiently transfected with GFP-tagged NR2A lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Teng H.J., et al. (2010) PLoS ONE. 5: e13342.

Product Datasheet

https://cdn.gentaur.com/products/400/4291422/datasheet/smc-434d-a488.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4291422/msds/smc-434d-a488.pdf

CAS Number

9007-83-4

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