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LRP4 (Extracellular) Antibody: RPE

Mouse Anti-Mouse LRP4 (Extracellular) Monoclonal IgG2A

Product Specifications

Background

Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

Specifications

Detects the extracellular domain of LRP4 ~215kDa. Degradation product can be seen at ~150kDa.

Product Name Alternative

Corin Antibody, KIAA0816 Antibody, LDLR Antibody, LDLR dan Antibody, Low density lipoprotein receptor related protein 4 Antibody, LRP-4 Antibody, LRP10 Antibody, MEGF7 Antibody, Multiple epidermal growth factor like domains 7 Antibody

Synonyms

LRP4 Antibody, Clone N207/27: RPE

UNSPSC

12352203

Gene ID

83469

Swiss Prot

Q8VI56

Accession Number

NP_766256.3

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

Target

LRP4

Clonality

Monoclonal

Isotype

IgG2A

Clone

N207/27 (Formerly sold as S207-27)

Conjugation

RPE

Validated Applications

WB,IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-418 was sufficient for detection of LRP4 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353–92.

Product Datasheet

https://cdn.gentaur.com/products/400/4291042/datasheet/smc-418d-rpe.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4291042/msds/smc-418d-rpe.pdf

CAS Number

9007-83-4

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