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VGLUT3 Antibody: RPE

Mouse Anti-Rat VGLUT3 Monoclonal IgG1

Product Specifications

Background

Vesicular Glutamate Transporter 3 (VGLUT3) is a multipass membrane protein restricted to synaptic vesicles of glutamergic neurons. It is specifically expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord, and thalamus. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.

Specifications

Detects ~65kDa.

Product Name Alternative

DFNA25 Antibody, Vesicular glutamate transporter 3 Antibody, deafness autosomal dominant 25 Antibody, SLC17A8 Antibody, Solute carrier family 17 member 8 Antibody, VGLUT 3 Antibody, Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8 Antibody

Synonyms

VGLUT3 Antibody, Clone N34/34: RPE

UNSPSC

12352203

Gene ID

266767

Swiss Prot

Q7TSF2

Accession Number

NP_714947.1

Cellular Locus

Cytoplasmic Vesicle | Secretory Vesicle | Synaptic Vesicle Membrane | Membrane | Cell Junction | Synapse

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 546-588 (cytoplasmic C-terminus) of rat VGLUT3

Target

VGLUT3

Clonality

Monoclonal

Isotype

IgG1

Clone

N34/34 (Formerly sold as S34-34)

Conjugation

RPE

Validated Applications

WB,IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-397 was sufficient for detection of VGLUT3 in 20 µg of CV-1 fibroblast cells (lysate) transfected with VGLUT3 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Amilhon B., et al. (2010) J Neurosci. 30(6): 2198-2210. 2. Herzog E., et al. (2004) Neurosci. 123(4): 983-1002.

Product Datasheet

https://cdn.gentaur.com/products/400/4290517/datasheet/smc-397d-rpe.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4290517/msds/smc-397d-rpe.pdf

CAS Number

9007-83-4

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