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VGLUT3 Antibody

Mouse Anti-Rat VGLUT3 Monoclonal IgG1

Product Specifications

Background

Vesicular Glutamate Transporter 3 (VGLUT3) is a multipass membrane protein restricted to synaptic vesicles of glutamergic neurons. It is specifically expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord, and thalamus. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.

Specifications

Detects ~65kDa.

Product Name Alternative

DFNA25 Antibody, Vesicular glutamate transporter 3 Antibody, deafness autosomal dominant 25 Antibody, SLC17A8 Antibody, Solute carrier family 17 member 8 Antibody, VGLUT 3 Antibody, Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8 Antibody

Synonyms

VGLUT3 Antibody, Clone N34/34

UNSPSC

12352203

Gene ID

266767

Swiss Prot

Q7TSF2

Accession Number

NP_714947.1

Cellular Locus

Cytoplasmic Vesicle | Secretory Vesicle | Synaptic Vesicle Membrane | Membrane | Cell Junction | Synapse

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 546-588 (cytoplasmic C-terminus) of rat VGLUT3

Target

VGLUT3

Clonality

Monoclonal

Isotype

IgG1

Clone

N34/34 (Formerly sold as S34-34)

Conjugation

Unconjugated

Validated Applications

WB,IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-397 was sufficient for detection of VGLUT3 in 20 µg of CV-1 fibroblast cells (lysate) transfected with VGLUT3 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Amilhon B., et al. (2010) J Neurosci. 30(6): 2198-2210. 2. Herzog E., et al. (2004) Neurosci. 123(4): 983-1002.

Product MSDS

https://cdn.gentaur.com/products/400/4290495/msds/smc-397d.pdf

CAS Number

9007-83-4

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