Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

VGLUT1 Antibody: FITC

Mouse Anti-Rat VGLUT1 Monoclonal IgG1

Product Specifications

Background

VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).

Specifications

Detects ~52kDa. No cross-reactivity against VGlut2.

Product Name Alternative

BNPI Antibody, SLC17A1 Antibody, SLC17A1/VGLUT1 Antibody, Solute Carrier family 17 member 7 Antibody, Vesicular glutamate transporter 1 Antibody, VGLUT 1 Antibody, Brain-specific Na(+)-dependent inorganic phosphate cotransporter Antibody

Synonyms

VGLUT1 Antibody, Clone N28/9: FITC

UNSPSC

12352203

Gene ID

116638

Swiss Prot

Q62634

Accession Number

NP_446311.1

Cellular Locus

Cytoplasmic Vesicle | Secretory Vesicle | Synaptic Vesicle Membrane | Membrane | Cell Junction | Synapse

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1

Target

VGLUT1

Clonality

Monoclonal

Isotype

IgG1

Clone

N28/9 (Formerly sold as S28-9)

Conjugation

FITC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-394 was sufficient for detection of VGLut1 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Wojcik S.M., et al. (2004) PNAS. 101(18): 7158-7163. 2. Shigeri Y., Seal R.P., Shimamoto K. (2004) Brain Res Rev. 45(3): 250-265.

Product Datasheet

https://cdn.gentaur.com/products/400/4290438/datasheet/smc-394d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4290438/msds/smc-394d-fitc.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GAMT (NM_000156) Human Tagged Lenti ORF Clone
RC200528L1 10 µg

GAMT (NM_000156) Human Tagged Lenti ORF Clone

Ask
View Details
Lenti ORF clone of MGC:5947 (mGFP-tagged) - Mouse cDNA clone MGC:5947 IMAGE:3491358 (BC002035) Mouse Tagged Lenti ORF Clone
MR202914L4 10 µg

Lenti ORF clone of MGC:5947 (mGFP-tagged) - Mouse cDNA clone MGC:5947 IMAGE:3491358 (BC002035) Mouse Tagged Lenti ORF Clone

Ask
View Details
Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic
MBS1255401-01 0.02 mg (E-Coli)

Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic

Ask
View Details
Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic
MBS1255401-02 0.1 mg (E-Coli)

Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic

Ask
View Details
Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic
MBS1255401-03 0.02 mg (Yeast)

Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic

Ask
View Details
Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic
MBS1255401-04 0.1 mg (Yeast)

Recombinant Brachypodium distachyon NAD (P)H-quinone oxidoreductase subunit K, chloroplastic

Ask
View Details