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VAChT Antibody: APC

Mouse Anti-Human VAChT Monoclonal IgG1

Product Specifications

Background

VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

Specifications

Detects ~56kDa.

Product Name Alternative

Vesicular Acetylcholine Transporter Antibody, MGC12716 Antibody, rVAT Antibody, Slc18a3 Antibody, Solute carrier family 18 (vesicular acetylcholine) member 3 Antibody, Solute carrier family 18 (vesicular monoamine) member 3 Antibody, Solute carrier family 18 member 3 Antibody

Synonyms

VAChT Antibody, Clone N6/38: APC

UNSPSC

12352203

Gene ID

6572

Swiss Prot

Q16572

Accession Number

NP_003046.2

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide amino acids 521-532 of human VAChT

Target

VAChT

Clonality

Monoclonal

Isotype

IgG1

Clone

N6/38 (Formerly sold as S6-38)

Conjugation

APC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

A dilution of 1:50-1:200 of SMC-393 was sufficient for detection of VAChT Transporter in rat brain using immunohistochemistry analysis and goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:200), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Erickson J.D., Varoqui H. (2000) FASEB J. 14(15): 2450-2458. 2. Weihe E., Tao-Cheng J.H., Schafer M.K., Erickson J.D., Eiden L.E. (1996) Proc Natl Acad Sci USA. 93(8): 3547-3552.

Product Datasheet

https://cdn.gentaur.com/products/400/4290405/datasheet/smc-393d-apc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4290405/msds/smc-393d-apc.pdf

CAS Number

9007-83-4

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