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GABA-A Receptor Alpha-1 Antibody: PerCP

Mouse Anti-Human GABA-A Receptor Alpha-1 Monoclonal IgG2A

Product Specifications

Background

The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).

Specifications

Detects ~55kDa. No cross-reactivity against GABA-A-R-Alpha 2 or –Alpha3.

Product Name Alternative

ECA4 antibody, EJM antibody, EJM5 antibody, Gaba receptor alpha 1 polypeptide antibody, GABA(A) receptor antibody, GABA(A) receptor subunit alpha 1 antibody, GABA(A) receptor subunit alpha-1 antibody, GABA(A) receptor, alpha 1 antibody, GABRA 1 antibody, GABRA1 antibody, Gamma aminobutyric acid (GABA) A receptor alpha 1 antibody, Gamma aminobutyric acid A receptor alpha 1 antibody, Gamma aminobutyric acid receptor subunit alpha 1 antibody, Gamma-aminobutyric acid receptor subunit alpha-1 antibody, GBRA1_HUMAN antibody

Synonyms

GABA A Receptor Alpha-1 Antibody, Clone N95/35: PerCP

UNSPSC

12352203

Gene ID

14394

Swiss Prot

P14867

Accession Number

NP_034380.1

Cellular Locus

Cell Membrane | Cell Junction | Synapse | Postsynaptic Cell Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Target

GABA A Receptor

Clonality

Monoclonal

Isotype

IgG2A

Clone

N95/35 (Formerly sold as S95-35)

Conjugation

PerCP

Validated Applications

WB,IHC,ICC/IF,ELISA

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-346 was sufficient for detection of alpha1 GABA receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136. 2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

Product Datasheet

https://cdn.gentaur.com/products/400/4290291/datasheet/smc-346d-pcp.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4290291/msds/smc-346d-pcp.pdf

CAS Number

9007-83-4

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