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GABA-A Receptor Delta Antibody: HRP

Mouse Anti-Rat GABA-A Receptor Delta Monoclonal IgG2a

Product Specifications

Background

The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).

Specifications

Detects ~55kDa.

Product Name Alternative

GABAA-RD Antibody, Gabrd Antibody, MGC105467 Antibody

Synonyms

GABA A Receptor Delta Antibody, Clone N151/3: HRP

UNSPSC

12352203

Gene ID

29689

Swiss Prot

P18506

Accession Number

NP_058985.1

Cellular Locus

Cell Membrane | Cell Junction | Synapse | Postsynaptic Cell Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide amino acids 15-34 (N-terminus) of rat GABA-A-R-Delta

Target

GABA A Receptor

Clonality

Monoclonal

Isotype

IgG2a

Clone

N151/3 (Formerly sold as S151-3)

Conjugation

HRP

Validated Applications

WB,IHC,ELISA

Purification

Protein G Purified

Limit Of Detection

2 µg/ml of SMC-345 was sufficient for detection of Delta1 GABA-A receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136. 2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

Product Datasheet

https://cdn.gentaur.com/products/400/4290264/datasheet/smc-345d-hrp.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4290264/msds/smc-345d-hrp.pdf

CAS Number

9007-83-4

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