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GABA-A Receptor Delta Antibody

Mouse Anti-Rat GABA-A Receptor Delta Monoclonal IgG2a

Product Specifications

Background

The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).

Specifications

Detects ~55kDa.

Product Name Alternative

GABAA-RD Antibody, Gabrd Antibody, MGC105467 Antibody

Synonyms

GABA A Receptor Delta Antibody, Clone N151/3

UNSPSC

12352203

Gene ID

29689

Swiss Prot

P18506

Accession Number

NP_058985.1

Cellular Locus

Cell Membrane | Cell Junction | Synapse | Postsynaptic Cell Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide amino acids 15-34 (N-terminus) of rat GABA-A-R-Delta

Target

GABA A Receptor

Clonality

Monoclonal

Isotype

IgG2a

Clone

N151/3 (Formerly sold as S151-3)

Conjugation

Unconjugated

Validated Applications

WB,ICC/IF,AM

Purification

Protein G Purified

Limit Of Detection

2 µg/ml of SMC-345 was sufficient for detection of Delta1 GABA-A receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136. 2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

Product MSDS

https://cdn.gentaur.com/products/400/4290245/msds/smc-345d.pdf

CAS Number

9007-83-4

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