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TrpV3 Antibody: PerCP

Mouse Anti-Rat TrpV3 Monoclonal IgG2a

Product Specifications

Background

The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).

Specifications

Detects ~70kDa.

Product Name Alternative

VRL3 Antibody, vanilloid receptor 2 Antibody, transient receptor potential cation channel subfamily V member 3 Antibody, sensitive channel TRPV3 Antibody, 1110036I10Rik Antibody, MGC124324 Antibody, MGC124325 Antibody, Trpv3 heat sensitive channel Antibody, vanilloid receptor-related osmotically activated channel protein Antibody

Synonyms

TRPV3 Antibody, Clone N15/39: PerCP

UNSPSC

12352203

Gene ID

497948

Swiss Prot

Q4QYD9

Accession Number

NP_001020928

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3

Target

TRPV3

Clonality

Monoclonal

Isotype

IgG2a

Clone

N15/39 (Formerly sold as S15-39)

Conjugation

PerCP

Validated Applications

WB,IHC,ICC/IF,ELISA

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-334 was sufficient for detection of TrpV3 in 10 µg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Masamoto Y., Kawabata F., Fushiki T. (2009) Biosci. Biotechnol. Biochem. 73(5): 1021-1027. 2. Xiao R., et al. (2008) J Biol Chem. 283(10): 6162-6174.

Product Datasheet

https://cdn.gentaur.com/products/400/4289991/datasheet/smc-334d-pcp.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4289991/msds/smc-334d-pcp.pdf

CAS Number

9007-83-4

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