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Slo2.2 Antibody

Mouse Anti-Rat Slo2.2 Monoclonal IgG1

Product Specifications

Background

Slo2.2 is a novel member of the mammalian Slo potassium channel gene family. Slo2 channels may contribute to the resting potentials of cells that control their basal level of excitability (1). They also have sensors that couple channel activity to the intracellular concentrations of Na+ and Cl- (2).

Specifications

Detects ~140kDa. Weak human detection. Does not cross-react with KCNT2/Slo2.1/Slick.

Product Name Alternative

KCNT1 Antibody, potassium channel subfamily T member 1 Antibody, bA100C15.2 Antibody, SLACK Antibody, KCa4.1KIAA1422FLJ41282 Antibody

Synonyms

Slo2.2 Antibody, Clone N3/26

UNSPSC

12352203

Gene ID

60444

Swiss Prot

Q9Z258

Accession Number

NP_068625

Cellular Locus

Cell Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 1168-1237 of rat Slo2.2 (Slack)

Target

Slo2.2

Clonality

Monoclonal

Isotype

IgG1

Clone

N3/26 (Formerly sold as S3-26)

Conjugation

Unconjugated

Validated Applications

WB,IHC,ICC/IF,AM

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-323 was sufficient for detection of Slo2.2 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.012

Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Santi C.M., et al. (2006) J Neuroscience, 26(19): 5059-5068. 2. Yuan A., et al. (2003) Neuron 37: 765-773.

Product MSDS

https://cdn.gentaur.com/products/400/4289719/msds/smc-323s.pdf

CAS Number

9007-83-4

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