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Kir2.1 Antibody: APC

Mouse Anti-Mouse Kir2.1 Monoclonal IgG1

Product Specifications

Background

The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil syndrome (1).

Specifications

Detects ~45kDa. No cross-reactivity against Kir2.2 or Kir2.3.

Product Name Alternative

HHBIRK1 Antibody, HHIRK1 Antibody, HIRK 1 Antibody, IRK1 Antibody, KCNJ2 Antibody, LQT7 Antibody, SQT3 Antibody, potassium inwardly rectifying channel J2 Antibody

Synonyms

Kir2.1 Antibody, Clone S112: APC

UNSPSC

12352203

Gene ID

16518

Swiss Prot

P35561

Accession Number

NP_032451

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat,Monkey

Immunogen

Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1

Target

Kir2.1

Clonality

Monoclonal

Isotype

IgG1

Clone

S112

Conjugation

APC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-310 was sufficient for detection of Kir2.1 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Donaldson M.R., Yoon G., Fu Y.H., Ptacek L.J. (2004). Ann. Med. 36 Suppl 1: 92–7.

Product Datasheet

https://cdn.gentaur.com/products/400/4289430/datasheet/smc-310d-apc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4289430/msds/smc-310d-apc.pdf

CAS Number

9007-83-4

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