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HCN1 Antibody: FITC

Mouse Anti-Rat HCN1 Monoclonal IgG1

Product Specifications

Background

Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulatons of cell excitability. Importantly, they contribute to spontaneous rhythmic activity in both the heart and brain (1).

Specifications

Detects ~100kDa. No cross-reactivity against HCN2.

Product Name Alternative

BCNG-1 Antibody, BCNG1 Antibody, Brain cyclic nucleotide gated channel 1 Antibody, Brain cyclic nucleotide-gated channel 1 Antibody, HAC2 Antibody, HCN1 Antibody, HCN1_HUMAN Antibody, Hyperpolarization activated cyclic nucleotide gated potassium channel 1 Antibody, Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 1 Antibody, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Antibody

Synonyms

HCN1 Antibody, Clone S70: FITC

UNSPSC

12352203

Gene ID

84390

Swiss Prot

Q9JKB0

Accession Number

NP_445827.1

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Target

HCN1

Clonality

Monoclonal

Isotype

IgG1

Clone

S70

Conjugation

FITC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-304 was sufficient for detection of HCN1 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Zong X., et al. (2005) J Biol Chem. 280(40): 34224-34232.

Product Datasheet

https://cdn.gentaur.com/products/400/4289288/datasheet/smc-304d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4289288/msds/smc-304d-fitc.pdf

CAS Number

9007-83-4

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