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Cav3.2 Antibody

Mouse Anti-Human Cav3.2 Monoclonal IgG1

Product Specifications

Background

CaV3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (1, 2). Studies also suggest that the up-regulations of CaV3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (3).

Specifications

Detects ~260kDa. No cross-reactivity against Cav1.3.

Product Name Alternative

Cav3.2 Antibody, CACNA1H Antibody, CACNA1HB Antibody, calcium channel Antibody, voltage-dependent Antibody, T type Antibody, alpha 1H subunit Antibody, calcium channel Antibody, voltage-dependent Antibody, T type Antibody, alpha 1Hb subunit Antibody, ECA6 Antibody, EIG6 Antibody, FLJ90484 Antibody, Low-voltage-activated calcium channel alpha1 3.2 subunit Antibody, low-voltage-activated calcium channel alpha13.2 subunit Antibody, voltage dependent t-type calcium channel alpha-1H subunit Antibody, voltage-dependent T-type calcium channel subunit alpha-1H Antibody, voltage-gated calcium channel alpha subunit Cav3.2 Antibody, voltage-gated calcium channel alpha subunit CavT.2 Antibody, Voltage-gated calcium channel subunit alpha Cav3.2 Antibody

Synonyms

Cav3.2 Antibody, Clone N55/10

UNSPSC

12352203

Gene ID

8912

Swiss Prot

O95180

Accession Number

NP_001005407.1

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2

Target

Cav3.2

Clonality

Monoclonal

Isotype

IgG1

Clone

N55/10 (Formerly sold as S55-10)

Conjugation

Unconjugated

Validated Applications

WB,IHC,ICC/IF,IP,AM

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-303 was sufficient for detection of Cav3.2 in 10 µg of HEK cell lysate expressing Cav3.2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.012

Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Chen Y., et al. (2003) Ann. Neurol. 54(2): 239–43. 2. Khosravani H., et al. (2004) J Biol Chem. 279(11): 9681-9684. 3. Gackiere F., et al. (2008) J Biol Chem. 283(28): 19872.

Product MSDS

https://cdn.gentaur.com/products/400/4289269/msds/smc-303s.pdf

CAS Number

9007-83-4

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