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Cav3.2 Antibody: RPE

Mouse Anti-Human Cav3.2 Monoclonal IgG1

Product Specifications

Background

CaV3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (1, 2). Studies also suggest that the up-regulations of CaV3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (3).

Specifications

Detects ~260kDa. No cross-reactivity against Cav1.3.

Product Name Alternative

Cav3.2 Antibody, CACNA1H Antibody, CACNA1HB Antibody, calcium channel Antibody, voltage-dependent Antibody, T type Antibody, alpha 1H subunit Antibody, calcium channel Antibody, voltage-dependent Antibody, T type Antibody, alpha 1Hb subunit Antibody, ECA6 Antibody, EIG6 Antibody, FLJ90484 Antibody, Low-voltage-activated calcium channel alpha1 3.2 subunit Antibody, low-voltage-activated calcium channel alpha13.2 subunit Antibody, voltage dependent t-type calcium channel alpha-1H subunit Antibody, voltage-dependent T-type calcium channel subunit alpha-1H Antibody, voltage-gated calcium channel alpha subunit Cav3.2 Antibody, voltage-gated calcium channel alpha subunit CavT.2 Antibody, Voltage-gated calcium channel subunit alpha Cav3.2 Antibody

Synonyms

Cav3.2 Antibody, Clone N55/10: RPE

UNSPSC

12352203

Gene ID

8912

Swiss Prot

O95180

Accession Number

NP_001005407.1

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2

Target

Cav3.2

Clonality

Monoclonal

Isotype

IgG1

Clone

N55/10 (Formerly sold as S55-10)

Conjugation

RPE

Validated Applications

WB,IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-303 was sufficient for detection of Cav3.2 in 10 µg of HEK cell lysate expressing Cav3.2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Chen Y., et al. (2003) Ann. Neurol. 54(2): 239–43. 2. Khosravani H., et al. (2004) J Biol Chem. 279(11): 9681-9684. 3. Gackiere F., et al. (2008) J Biol Chem. 283(28): 19872.

Product Datasheet

https://cdn.gentaur.com/products/400/4289267/datasheet/smc-303d-rpe.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4289267/msds/smc-303d-rpe.pdf

CAS Number

9007-83-4

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