Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AHA1 Antibody

Rat Anti-Mouse AHA1 Monoclonal IgG2a Kappa

Product Specifications

Background

Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).

Specifications

Detects ~38kDa. Can run up to 45kDa on SDS Page.

Product Name Alternative

Aha 1 Antibody, Ahsa1 Antibody, p38 Antibody, HSPC322 Antibody, C14orf3 Antibody, Activator of HSP90 ATPase Antibody, Activator of 90 kDa heat shock protein ATPase homolog 1 Antibody

Synonyms

AHA1 Antibody, Clone 25F2.D9: Streptavidin

UNSPSC

12352203

Gene ID

217737

Swiss Prot

Q8BK64

Accession Number

NP_666148.1

Cellular Locus

Cytoplasm | Endoplasmic Reticulum

Host

Rat

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant Full Length Mouse Aha1 Protein

Target

AHA1

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

25F2.D9

Conjugation

Unconjugated

Validated Applications

WB,IHC,ICC/IF,IP,ELISA

Purification

Protein G Purified

Limit Of Detection

1 µg/ml of SMC-172 was sufficient for detection of Aha1 in 10 µg of rat tissue lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody.

Concentration

1.2 mg/ml

Dilution

WB (1:1000), IHC (1:100), ICC/IF (1:1000), IP (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.012

Buffer

0.02M potassium phosphate, 0.15M sodium chloride, pH7.2

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Hainzl O., Lapina M.C., Buchner J., Richter K. (2009) J Biol Chem. Epub. 2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt.3): 789-796. 3. Lotz G.P., Brychzy A., Heinz S., Obermann W.M. (2008) J Cell Sci. 121(pt.5): 717-723. 4. Holmes J.L., Sharp S.Y., Hobbs S., Workman P. (2008) Cancer Res. 68(4): 1188-1197.

Product MSDS

https://cdn.gentaur.com/products/400/4287448/msds/smc-172s.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Research Grade Gocatamig
HP628086-01 100 µg

Research Grade Gocatamig

Ask
View Details
Research Grade Gocatamig
HP628086-02 1 mg

Research Grade Gocatamig

Ask
View Details
Rabbit Polyclonal Cerebellin-1/Precerebellin Antibody [Alexa Fluor 488]
NBP1-77238AF488 0.1 mL

Rabbit Polyclonal Cerebellin-1/Precerebellin Antibody [Alexa Fluor 488]

Ask
View Details
MAPK14 antibody
FNab06077 100 µg

MAPK14 antibody

Ask
View Details
VKORC1 Protein Lysate (Human) with C-Ha Tag
49511031 100 μg

VKORC1 Protein Lysate (Human) with C-Ha Tag

Ask
View Details
Recombinant Enterobacteria phage T4 Large tail fiber protein p34 (34), partial
MBS1180635 Inquire

Recombinant Enterobacteria phage T4 Large tail fiber protein p34 (34), partial

Ask
View Details