Amitraz

Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis[1][2].

Product Specifications

CAS Number

[33089-61-1]

Product Name Alternative

BTS-27419

UNSPSC

12352005

Hazard Statement

H302, H317, H373

Target

Adrenergic Receptor; Monoamine Oxidase; Parasite

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Amitraz.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN(/C=N/C1=CC=C(C)C=C1C)/C=N/C2=CC=C(C)C=C2C

Molecular Formula

C19H23N3

Molecular Weight

293.41

Precautions

H302, H317, H373

References & Citations

[1]Mangia C, et al. Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line. Parasit Vectors. 2018 Jul 31;11 (1) :437. |[2]Kim JC, et al. Evaluation of developmental toxicity of amitraz in Sprague-Dawley rats. Arch Environ Contam Toxicol. 2007 Jan;52 (1) :137-44.