Z-VA-DL-D-FMK
Product Specifications
UNSPSC Description
Z-VA-DL-D-FMK (Z-VA-DL-D(OH)-FMK) is an inhibitor for caspase[1]. Z-VA-DL-D-FMK binds irreversibly to caspases, increases the sensitivity of TNF-α, and activates HIV replication in infected T cell ACH-2[1].
Target Antigen
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/z-va-dl-d-fmk.html
Smiles
O=C(CF)C(NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)CC(O)=O
Molecular Weight
453.46
References & Citations
[1]Scheller C, et al., Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95. J Biol Chem. 2002 May 3;277(18):15459-64.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16658C/Z-VA-DL-D-FMK-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16658C/
Clinical Information
No Development Reported
CAS Number
220644-02-0
Curated Selection
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