Hexylresorcinol

Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage[1][2][3][4][5].

Product Specifications

CAS Number

[136-77-6]

Product Name Alternative

4-Hexylresorcinol

UNSPSC

12352005

Hazard Statement

H302, H319, H411

Target

Apoptosis; Bacterial; Endogenous Metabolite; Glycosidase; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Hexylresorcinol.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(CCCCCC)C(O)=C1

Molecular Formula

C12H18O2

Molecular Weight

194.27

Precautions

H302, H319, H411

References & Citations

[1]Y. A. Nikolaev, et al. The use of 4-Hexylresorcinol as antibiotic adjuvant. PLoS One. 2020; 15 (9) : e0239147.|[2]Seong-Gon Kim, et al. 4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers. Oncol Rep. 2013 May;29 (5) :1835-40.|[3]Shuang Song, et al. Inhibitory potential of 4-hexylresorcinol against α-glucosidase and non-enzymatic glycation: Activity and mechanism. J Biosci Bioeng. 2020 Nov 12; S1389-1723 (20) 30400-X.|[4]Gow-Chin Yen, et al. Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocyte. Free Radic Res. 2003 May;37 (5) :509-14.|[5]Min-Keun Kim, et al. 4-Hexylresorcinol induced angiogenesis potential in human endothelial cells. Maxillofac Plast Reconstr Surg. 2020 Dec; 42 (1) : 23.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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