Z280B Polyclonal Antibody

Rabbit Anti-Z280B Polyclonal Antibody

Product Specifications

Background

The protein encoded by ZNF280B (Zinc Finger Protein 280B) is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. ZNF280B is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for ZNF280B, but only one of them is protein-coding.

CAS Number

9007-83-4

Product Name Alternative

Zinc finger protein 280B; 5'OY11.1; Suppressor of hairy wing homolog 2; Zinc finger protein 279; Zinc finger protein 632

Gene ID

140883

Accession Number

Q86YH2

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human Z280B protein

Clonality

Polyclonal

Tag

Z280B

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

59kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of Z280B protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000