VMAT2 Polyclonal Antibody

Rabbit Anti-VMAT2 Polyclonal Antibody

Product Specifications

Background

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al. 1993 [PubMed 7905859]) . See also SLC18A1 (MIM 193002) .

CAS Number

9007-83-4

Product Name Alternative

Monoamine transporter; Solute carrier family 18 member 2; Vesicular amine transporter 2; VAT2

Gene ID

6571

Accession Number

Q05940

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human VMAT2 protein at amino acid sequence of 1-80

Clonality

Polyclonal

Tag

VMAT2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

56kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of VMAT2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000