VANG2 Polyclonal Antibody

Rabbit Anti-VANG2 Polyclonal Antibody

Product Specifications

Background

VANGL2 (VANGL Planar Cell Polarity Protein 2) is a Protein Coding gene. Diseases associated with VANGL2 include Neural Tube Defects and Vangl2-Related Neural Tube Defect. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Wnt Signaling Pathway and Pluripotency. The protein encoded by VANGL2 is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.

CAS Number

9007-83-4

Product Name Alternative

Vang-like protein 2; Loop-tail protein 1 homolog; Strabismus 1; Van Gogh-like protein 2

Gene ID

57216

Accession Number

Q9ULK5

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human VANG2 protein

Clonality

Polyclonal

Tag

VANG2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of VANG2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000