UNC5D Polyclonal Antibody

Rabbit Anti-UNC5D Polyclonal Antibody

Product Specifications

Background

Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed: 24519068) . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.

CAS Number

9007-83-4

Product Name Alternative

Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D

Gene ID

137970

Accession Number

Q6UXZ4

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human UNC5D protein at amino acid sequence of 160-240

Clonality

Polyclonal

Tag

UNC5D

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

104kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of UNC5D protein

Observed Molecular Weight

104

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000