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UB2L6 Polyclonal Antibody

Rabbit Anti-UB2L6 Polyclonal Antibody

Product Specifications

Background

UBE2L6 (Ubiquitin Conjugating Enzyme E2 L6) is a Protein Coding gene. Among its related pathways are Proteolysis_Putative ubiquitin pathway and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . UBE2L6 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for UBE2L6.

CAS Number

9007-83-4

Product Name Alternative

Ubiquitin/ISG15-conjugating enzyme E2 L6; E2 ubiquitin-conjugating enzyme L6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6

Gene ID

9246

Accession Number

O14933

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human UB2L6 protein

Clonality

Polyclonal

Tag

UB2L6

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

16kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of UB2L6 protein

Observed Molecular Weight

16

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Ubiquitin/ISG15-conjugating enzyme E2 L6; E2 ubiquitin-conjugating enzyme L6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O14933

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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