TRPV6 Polyclonal Antibody
Rabbit Anti-TRPV6 Polyclonal Antibody
Product Specifications
Background
TRPV6 (Transient Receptor Potential Cation Channel Subfamily V Member 6) is a Protein Coding gene. Diseases associated with TRPV6 include Prostate Cancer and Aromatase Deficiency. Among its related pathways are TRP channels and Mineral absorption. TRPV6 encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. TRPV6 is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5) . This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
CAS Number
9007-83-4
Product Name Alternative
Transient receptor potential cation channel subfamily V member 6; TrpV6; CaT-like; CaT-L; Calcium transport protein 1; CaT1; Epithelial calcium channel 2; ECaC2
Gene ID
55503
Accession Number
Q9H1D0
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human TRPV6 protein
Clonality
Polyclonal
Tag
TRPV6
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
79kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of TRPV6 protein
Observed Molecular Weight
79
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Transient receptor potential cation channel subfamily V member 6; TrpV6; CaT-like; CaT-L; Calcium transport protein 1; CaT1; Epithelial calcium channel 2; ECaC2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9H1D0
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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