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TRPV6 Polyclonal Antibody

Rabbit Anti-TRPV6 Polyclonal Antibody

Product Specifications

Background

TRPV6 (Transient Receptor Potential Cation Channel Subfamily V Member 6) is a Protein Coding gene. Diseases associated with TRPV6 include Prostate Cancer and Aromatase Deficiency. Among its related pathways are TRP channels and Mineral absorption. TRPV6 encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. TRPV6 is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5) . This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.

CAS Number

9007-83-4

Product Name Alternative

Transient receptor potential cation channel subfamily V member 6; TrpV6; CaT-like; CaT-L; Calcium transport protein 1; CaT1; Epithelial calcium channel 2; ECaC2

Gene ID

55503

Accession Number

Q9H1D0

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human TRPV6 protein

Clonality

Polyclonal

Tag

TRPV6

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

79kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of TRPV6 protein

Observed Molecular Weight

79

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Transient receptor potential cation channel subfamily V member 6; TrpV6; CaT-like; CaT-L; Calcium transport protein 1; CaT1; Epithelial calcium channel 2; ECaC2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9H1D0

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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