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SYNE2 Polyclonal Antibody

Rabbit Anti-SYNE2 Polyclonal Antibody

Product Specifications

Background

SYNE2 (Spectrin Repeat Containing Nuclear Envelope Protein 2) is a Protein Coding gene. Diseases associated with SYNE2 include Emery-Dreifuss Muscular Dystrophy 5, Autosomal Dominant and Emery-Dreifuss Muscular Dystrophy 2, Ad. Among its related pathways are Meiosis and Ovarian Infertility Genes. The protein encoded by SYNE2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus.

CAS Number

9007-83-4

Product Name Alternative

Nesprin-2; KASH domain-containing protein 2; KASH2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; Protein NUANCE; Synaptic nuclear envelope protein 2; Syne-2

Gene ID

23224

Accession Number

Q8WXH0

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human SYNE2 protein at amino acid sequence of 360-440

Clonality

Polyclonal

Tag

SYNE2

Applications

IHC, IF

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

757kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SYNE2 protein

Observed Molecular Weight

757

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200

Other Product Names

Nesprin-2; KASH domain-containing protein 2; KASH2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; Protein NUANCE; Synaptic nuclear envelope protein 2; Syne-2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q8WXH0

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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