STAR Polyclonal Antibody

Rabbit Anti-STAR Polyclonal Antibody

Product Specifications

Background

The protein encoded by STAR plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in STAR are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of STAR is located on chromosome 13.

CAS Number

9007-83-4

Product Name Alternative

Steroidogenic acute regulatory protein, mitochondrial; StAR; START domain-containing protein 1; StARD1

Gene ID

6770

Accession Number

P49675

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human STAR protein

Clonality

Polyclonal

Tag

STAR

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

31kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of STAR protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Steroidogenic acute regulatory protein, mitochondrial; StAR; START domain-containing protein 1; StARD1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P49675

Isotype

Rabbit IgG

Available Sizes

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