SPG7 Polyclonal Antibody

Rabbit Anti-SPG7 Polyclonal Antibody

Product Specifications

Background

SPG7 encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in SPG7 cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

CAS Number

9007-83-4

Product Name Alternative

Paraplegin; Cell matrix adhesion regulator; Spastic paraplegia 7 protein

Gene ID

6687

Accession Number

Q9UQ90

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human SPG7 protein at amino acid sequence of 71-120

Clonality

Polyclonal

Tag

SPG7

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

87kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SPG7 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000