SC5A5 Polyclonal Antibody

Rabbit Anti-SC5A5 Polyclonal Antibody

Product Specifications

Background

SLC5A5 (Solute Carrier Family 5 Member 5) is a Protein Coding gene. Diseases associated with SLC5A5 include Thyroid Dyshormonogenesis 1 and Familial Thyroid Dyshormonogenesis. Among its related pathways are Insulin secretion and Metabolism. SLC5A5 encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4) . Mutations in SLC5A5 are associated with thyroid dyshormonogenesis 1.

CAS Number

9007-83-4

Product Name Alternative

Sodium/iodide cotransporter; Na (+) /I (-) cotransporter; Sodium-iodide symporter; Na (+) /I (-) symporter; Solute carrier family 5 member 5

Gene ID

6528

Accession Number

Q92911

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human SC5A5 protein

Clonality

Polyclonal

Tag

SC5A5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

70kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SC5A5 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000