RPC10 Polyclonal Antibody
Rabbit Anti-RPC10 Polyclonal Antibody
Product Specifications
Background
POLR3K encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17. POLR3K (RNA Polymerase III Subunit K) is a Protein Coding gene. Diseases associated with POLR3K include Spherocytosis, Type 5. Among its related pathways are Pyrimidine metabolism (KEGG) and RNA Polymerase III Transcription Initiation.
CAS Number
9007-83-4
Product Name Alternative
DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerase III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C11
Gene ID
51728
Accession Number
Q9Y2Y1
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RPC10 protein
Clonality
Polyclonal
Tag
RPC10
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
11kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RPC10 protein
Observed Molecular Weight
11
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerase III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C11
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y2Y1
Isotype
Rabbit IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items