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RPC10 Polyclonal Antibody

Rabbit Anti-RPC10 Polyclonal Antibody

Product Specifications

Background

POLR3K encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17. POLR3K (RNA Polymerase III Subunit K) is a Protein Coding gene. Diseases associated with POLR3K include Spherocytosis, Type 5. Among its related pathways are Pyrimidine metabolism (KEGG) and RNA Polymerase III Transcription Initiation.

CAS Number

9007-83-4

Product Name Alternative

DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerase III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C11

Gene ID

51728

Accession Number

Q9Y2Y1

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human RPC10 protein

Clonality

Polyclonal

Tag

RPC10

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

11kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RPC10 protein

Observed Molecular Weight

11

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerase III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C11

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9Y2Y1

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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