RN135 Polyclonal Antibody

Rabbit Anti-RN135 Polyclonal Antibody

Product Specifications

Background

The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RNF135 is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

CAS Number

9007-83-4

Product Name Alternative

E3 ubiquitin-protein ligase RNF135; RIG-I E3 ubiquitin ligase; REUL; RING finger protein 135; RING-type E3 ubiquitin transferase RNF135; Riplet

Gene ID

84282

Accession Number

Q8IUD6

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human RN135 protein at amino acid sequence of 81-130

Clonality

Polyclonal

Tag

RN135

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

47kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RN135 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000