REV1 Polyclonal Antibody

Rabbit Anti-REV1 Polyclonal Antibody

Product Specifications

Background

REV1 encodes REV1, DNA Directed Polymerase with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

CAS Number

9007-83-4

Product Name Alternative

DNA repair protein REV1; Alpha integrin-binding protein 80; AIBP80; Rev1-like terminal deoxycytidyl transferase

Gene ID

51455

Accession Number

Q9UBZ9

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human REV1 protein

Clonality

Polyclonal

Tag

REV1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

137kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of REV1 protein

Observed Molecular Weight

137

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000