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RASM Polyclonal Antibody

Rabbit Anti-RASM Polyclonal Antibody

Product Specifications

Background

MRAS encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. MRAS (Muscle RAS Oncogene Homolog) is a Protein Coding gene. Diseases associated with MRAS include Vertebral Artery Occlusion and Causalgia. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and p70S6K Signaling.

CAS Number

9007-83-4

Product Name Alternative

Ras-related protein M-Ras; Ras-related protein R-Ras3

Gene ID

22808

Accession Number

O14807

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human RASM protein

Clonality

Polyclonal

Tag

RASM

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

22kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RASM protein

Observed Molecular Weight

22

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Ras-related protein M-Ras; Ras-related protein R-Ras3

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O14807

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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