PPR3D Polyclonal Antibody

Rabbit Anti-PPR3D Polyclonal Antibody

Product Specifications

Background

Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. PPP1R3D (Protein Phosphatase 1 Regulatory Subunit 3D) encodes a glycogen-targeting subunit of PP1.

CAS Number

9007-83-4

Product Name Alternative

Protein phosphatase 1 regulatory subunit 3D; Protein phosphatase 1 regulatory subunit 6; PP1 subunit R6; Protein phosphatase 1-binding subunit R6

Gene ID

5509

Accession Number

O95685

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human PPR3D protein at amino acid sequence of 10-90

Clonality

Polyclonal

Tag

PPR3D

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

32kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PPR3D protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000