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PPM1B Polyclonal Antibody

Rabbit Anti-PPM1B Polyclonal Antibody

Product Specifications

Background

The protein encoded by PPM1B is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Product Name Alternative

Protein phosphatase 2C isoform beta; PP2C-beta

Gene ID

5495

Accession Number

O75688

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human PPM1B protein at amino acid sequence of 310-390

Clonality

Polyclonal

Tag

PPM1B

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

52kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PPM1B protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP59983.pdf

Observed Molecular Weight

52

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Protein phosphatase 2C isoform beta; PP2C-beta

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O75688

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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