PLK4 Polyclonal Antibody

Rabbit Anti-PLK4 Polyclonal Antibody

Product Specifications

Background

PLK4 (Polo Like Kinase 4) is a Protein Coding gene. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for PLK4.

CAS Number

9007-83-4

Product Name Alternative

Serine/threonine-protein kinase PLK4; Polo-like kinase 4; PLK-4; Serine/threonine-protein kinase 18; Serine/threonine-protein kinase Sak

Gene ID

10733

Accession Number

O00444

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human PLK4 protein

Clonality

Polyclonal

Tag

PLK4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

106kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PLK4 protein

Observed Molecular Weight

106

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000