PILRB Polyclonal Antibody

Rabbit Anti-PILRB Polyclonal Antibody

Product Specifications

Background

The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. PILRB is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function.

CAS Number

9007-83-4

Product Name Alternative

Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR-beta; Cell surface receptor FDFACT

Gene ID

29990

Accession Number

Q9UKJ0

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human PILRB protein at amino acid sequence of 170-250

Clonality

Polyclonal

Tag

PILRB

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

24kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PILRB protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000