PGFRL Polyclonal Antibody

Rabbit Anti-PGFRL Polyclonal Antibody

Product Specifications

Background

PDGFRL encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing PDGFRL, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL product may function as a tumor suppressor.

CAS Number

9007-83-4

Product Name Alternative

Platelet-derived growth factor receptor-like protein; PDGFR-like protein; PDGF receptor beta-like tumor suppressor

Gene ID

5157

Accession Number

Q15198

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human PGFRL protein at amino acid sequence of 50-130

Clonality

Polyclonal

Tag

PGFRL

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

41kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PGFRL protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000