PD-L2 Polyclonal Antibody

Rabbit Anti-PD-L2 Polyclonal Antibody

Product Specifications

Background

PDCD1LG2 (Programmed Cell Death 1 Ligand 2) is a Protein Coding gene. Diseases associated with PDCD1LG2 include Cysticercosis and Myasthenic Syndrome, Congenital, 14, With Tubular Aggregates. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Translocation of ZAP-70 to Immunological synapse. An important paralog of this gene is CD274. Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .

CAS Number

9007-83-4

Product Name Alternative

Programmed cell death 1 ligand 2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD antigen CD273

Gene ID

80380

Accession Number

Q9BQ51

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human PD-L2 protein at amino acid sequence of 31-80

Clonality

Polyclonal

Tag

PD-L2

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

30kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PD-L2

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200