PDCD2 Polyclonal Antibody

Rabbit Anti-PDCD2 Polyclonal Antibody

Product Specifications

Background

PDCD2 (Programmed Cell Death 2) is a Protein Coding gene. Diseases associated with PDCD2 include Chronic Fatigue Syndrome and Type 1 Diabetes Mellitus 10. PDCD2 encodes a nuclear protein expressed in a variety of tissues. Expression of PDCD2 has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.

CAS Number

9007-83-4

Product Name Alternative

Programmed cell death protein 2; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8

Gene ID

5134

Accession Number

Q16342

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human PDCD2 protein at amino acid sequence of 180-260

Clonality

Polyclonal

Tag

PDCD2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

37kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PDCD2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000