PCF11 Polyclonal Antibody

Rabbit Anti-PCF11 Polyclonal Antibody

Product Specifications

Background

PCF11 (PCF11 Cleavage And Polyadenylation Factor Subunit) is a Protein Coding gene. Among its related pathways are mRNA surveillance pathway and Formation of HIV elongation complex in the absence of HIV Tat. The protein encoded by PCF11 binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage.

CAS Number

9007-83-4

Product Name Alternative

Pre-mRNA cleavage complex 2 protein Pcf11; Pre-mRNA cleavage complex II protein Pcf11

Gene ID

51585

Accession Number

O94913

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human PCF11 protein at amino acid sequence of 490-570

Clonality

Polyclonal

Tag

PCF11

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

171kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PCF11 protein

Observed Molecular Weight

171

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000